The Poppi Trial officially launched on the 15th September, and recruitment is now underway! The trial will take place over 3 years and aims to recruit 156 infants. It is a single centre randomised placebo-controlled trial investigating the efficacy of morphine analgesia for procedural pain in infants. The protocol was published in the Lancet and can… Continue reading Poppi Trial Launch!
We are going to begin recruitment for the Poppi trial soon. Poppi is a randomised controlled trial investigating the use of morphine as an analgesic for procedural pain in infants. The protocol for the trial has been published in The Lancet and can be viewed here: Hartley C, Moultrie F, Juszczak E, Adams E & Slater R. (2016) Protocol… Continue reading The Poppi Trial – Protocol Publication
A new publication for the PiPA group! Citation: Poorun R, Hartley C, Goksan S, Worley A, Boyd S, Cornelissen L, Berde C, Rogers R, Ali T, Slater R.(2015) Electroencephalography during general anaesthesia differs between term-born and premature-born children. Clin Neurophysiol. doi: 10.1016/j.clinph.2015.10.041. [Epub ahead of print] Abstract: Objectives: Premature birth is associated with a wide range of… Continue reading Electroencephalography During General Anaesthesia Differs Between Term-Born and Premature-Born Children.
A new publication for the PiPA group! Citation: Hartley C, Goksan S, Poorun R, Brotherhood K, Mellado GS, Moultrie F, Rogers R, Adams E, Slater R. (2015) The relationship between nociceptive brain activity, spinal reflex withdrawal and behaviour in newborn infants. Sci Rep. 5:12519. doi: 10.1038/srep12519. Abstract: Measuring infant pain is complicated by their inability to describe… Continue reading The Relationship Between Nociceptive Brain Activity, Spinal Reflex Withdrawal and Behaviour in Newborn Infants
A new publication for the PiPA group! This technical journal article describes the methods behind our ‘time-locking’ techniques. Citation: Worley A, Fabrizi L, Boyd S & Slater R (2012) Multi-modal pain measurements in infants. Journal of Neuroscience Methods. 205(2):252-257. Abstract: A non-invasive integrated method was developed to measure neural and behavioural responses to peripheral sensory and noxious stimulation… Continue reading Multi-Modal Pain Measurements in Infants
Earlier this evening, the latest of PiPA group’s articles was published in the Journal of Visualized Experiments. This technical journal article describes the methods behind our ‘time-locking’ techniques. Citation: Fabrizi L, Worley A, Patten D, Cornelissen L, Meek J, Boyd S & Slater R (2011) Electrophysiological measurements and analysis of nociception in human infants. JoVE. Abstract:… Continue reading Electrophysiological Measurements and Analysis of Nociception in Human Infants