Animation

How do babies feel pain?

An exciting new animation has been produced by Dr Fiona Moultrie, a member of the PiPA Group, describing how infants feel pain. It also includes ways in which we measure pain in babies as a group. Animation by Charlotte Moultrie. Follow Joe’s Journey below. Advertisements

Protocols · publications

The Poppi Trial – Protocol Publication

We are going to begin recruitment for the Poppi trial soon. Poppi is a randomised controlled trial investigating the use of morphine as an analgesic for procedural pain in infants. The protocol for the trial has been published in The Lancet and can be viewed here: Hartley C, Moultrie F, Juszczak E, Adams E & Slater R. (2016) Protocol… Continue reading The Poppi Trial – Protocol Publication

publications

Electroencephalography During General Anaesthesia Differs Between Term-Born and Premature-Born Children.

A new publication for the PiPA group! Citation: Poorun R, Hartley C, Goksan S, Worley A, Boyd S, Cornelissen L, Berde C, Rogers R, Ali T, Slater R.(2015) Electroencephalography during general anaesthesia differs between term-born and premature-born children. Clin Neurophysiol. doi: 10.1016/j.clinph.2015.10.041. [Epub ahead of print]   Abstract: Objectives: Premature birth is associated with a wide range of… Continue reading Electroencephalography During General Anaesthesia Differs Between Term-Born and Premature-Born Children.

publications

The Relationship Between Nociceptive Brain Activity, Spinal Reflex Withdrawal and Behaviour in Newborn Infants

A new publication for the PiPA group! Citation: Hartley C, Goksan S, Poorun R, Brotherhood K, Mellado GS, Moultrie F, Rogers R, Adams E, Slater R. (2015) The relationship between nociceptive brain activity, spinal reflex withdrawal and behaviour in newborn infants. Sci Rep. 5:12519. doi: 10.1038/srep12519.   Abstract: Measuring infant pain is complicated by their inability to describe… Continue reading The Relationship Between Nociceptive Brain Activity, Spinal Reflex Withdrawal and Behaviour in Newborn Infants

publications

Multi-Modal Pain Measurements in Infants

A new publication for the PiPA group! This technical journal article describes the methods behind our ‘time-locking’ techniques. Citation:  Worley A, Fabrizi L, Boyd S & Slater R (2012) Multi-modal pain measurements in infants. Journal of Neuroscience Methods. 205(2):252-257. Abstract: A non-invasive integrated method was developed to measure neural and behavioural responses to peripheral sensory and noxious stimulation… Continue reading Multi-Modal Pain Measurements in Infants

publications

Electrophysiological Measurements and Analysis of Nociception in Human Infants

Earlier this evening, the latest of PiPA group’s articles was published in the Journal of Visualized Experiments. This technical journal article describes the methods behind our ‘time-locking’ techniques. Citation:  Fabrizi L, Worley A, Patten D, Cornelissen L, Meek J, Boyd S & Slater R (2011) Electrophysiological measurements and analysis of nociception in human infants. JoVE. Abstract:… Continue reading Electrophysiological Measurements and Analysis of Nociception in Human Infants