Publications include Research Articles, Published Protocols, Reviews & Letters and Book Chapters & Published Abstracts.

All journal articles are open access and freely available. If you are having trouble viewing the journal articles then please contact us and we will be able to help you.

Published Protocols

PoppiLogoHartley C, Moultrie F, Juszczak E, Adams E & Slater R. (2016) Protocol 15PRT/5747: A blinded randomised placebo-controlled trial investigating the efficacy of morphine analgesia for procedural pain in infantsThe Lancet.

Slater R, Hartley 1, Moultrie F, Adams E, Juszczak E, Rogers R, Norman JE, Patel C, Stanbury K, Hoskin A, Green G, Poppi Trial Team (2016) A blinded randomised placebo-controlled trial investigating the efficacy of morphine analgesia for procedural pain in infants: Trial protocol. Wellcome Open Research.


Research Articles


Hartley C, Duff EP, Green G, Mellado GS, Worley A, Rogers R, Slater R (2017) Nociceptive brain activity as a measure of analgesic efficacy in infantsScience Translational Medicine. 3;9(388)


Goksan S, Hartley C, Hurley SA, Winkler AM, Duff EP, Jenkinson M, Rogers R, Clare S, Slater R (2016) Optimal echo time for functional MRI of the infant brain identified in response to noxious stimulation. Magnetic Resonance in Medicine. [epub ahead of print]

Hartley C, Moultrie F, Gursul D, Hoskin A, Adams E, Rogers R, Slater R. (2016) Changing Balance of Spinal Cord Excitability and Nociceptive Brain Activity in Early Human DevelopmentCurrent Biology. 26(15):1998-2002, 8 August 2016

Poorun R, Hartley C, Goksan S, Worley A, Boyd S, Cornelissen L, Berde C, Rogers R, Ali T, Slater R. (2016) Electroencephalography during general anaesthesia differs between term-born and premature-born children. Clin Neurophysiol127(2):1216-22. doi: 10.1016


Hartley C, Goksan S, Poorun R, Brotherhood K, Schmidt Mellado G, Moultrie F, Rogers R, Adams E, Slater R. (2015) The relationship between nociceptive brain activity, spinal reflex withdrawal and behaviour in newborn infants. Sci Rep. 5:12519. doi: 10.1038/srep12519.

Goksan S, Hartley C, Emery F, Cockrill N, Poorun R, Moultrie F, Rogers R, Campbell J, Sanders M, Adams E, Clare S, Jenkinson M, Tracey I, Slater R. (2015) fMRI reveals neural activity overlap between adult and infant pain. Elife. 4. doi: 10.7554/eLife.06356. Erratum in: Elife. 2015;4. doi: 10.7554/eLife.08663.

Williams G, Fabrizi L, Meek J, Jackson D, Tracey I, Robertson N, Slater R, Fitzgerald M.(2015) Functional magnetic resonance imaging can be used to explore tactile and nociceptive processing in the infant brain. Acta Paediatr. 104(2):158-66. doi: 10.1111/apa.12848.


Hartley C, Poorun R, Goksan S, Worley A, Boyd S, Rogers R, Ali T, Slater R. (2014) Noxious stimulation in children receiving general anaesthesia evokes an increase in delta frequency brain activity. Pain. 155(11):2368-76. doi: 10.1016/j.pain.2014.09.006.


Cornelissen L, Fabrizi L, Patten D, Worley A, Meek J, Boyd S, Slater R, Fitzgerald  M. (2013) Postnatal temporal, spatial and modality tuning of nociceptive cutaneous flexion reflexes in human infants. PLoS One. 8(10):e76470. doi: 10.1371/journal.pone.0076470.

Fabrizi L, Williams G, Lee A, Meek J, Slater R, Olhede S, Fitzgerald M. (2013) Cortical activity evoked by an acute painful tissue-damaging stimulus in healthy adult volunteers. J Neurophysiol. 109(9):2393-403. doi: 10.1152/jn.00990.2012.


Wilkinson D, Savulescu J & Slater R (2012) Sugaring the pill: ethics and uncertainties in the use of sucrose for newborn infants. Archives of Pediatrics & Adolescent Medicine. 166(7):629-33.

Worley A, Fabrizi L, Boyd S & Slater R (2012) Multi-modal pain measurements in infantsJournal of Neuroscience Methods. 205(2):252-257.


Fabrizi L, Worley A, Holdridge S, Patten D, Cornelissen L, Meek J, Boyd S & Slater R (2011) Electrophysiological measurements and analysis of nociception in human infantsJoVE.

Fabrizi L, Slater R, Worley A, Meek J, Boyd S, Olhede S & Fitzgerald M (2011) A Shift in Sensory Processing that Enables the Developing Human Brain to Discriminate Touch from PainCurrent Biology. 21(18):1552-1558.


Slater R, Cornelissen L, Fabrizi L, Patten D, Yoxen J, Worley A, Boyd S, Meek J, Boyd S & Fitzgerald M (2010) Oral sucrose as an analgesic drug for procedural pain in newborn infants: a randomised controlled trialThe Lancet. 376(9748):1225-1232.

Slater R, Fabrizi L, Worley A, Meek J, Boyd S & Fitzgerald M (2010) Premature infants display increased noxious evoked neuronal activity in the brain compared to healthy age-matched term-born infantsNeuroImage. 54:583-589.

Slater R, Worley A, Fabrizi L, Roberts S, Boyd S, Meek J & Fitzgerald M (2010) Evoked Potentials generated by noxious stimulation in the human infant brainEuropean Journal of Pain. 14:321-326.


Slater R, Cantarella A, Patten D, Yoxen J, Potts H, Meek J & Fitzgerald M (2009) Latency to facial expression change following noxious stimulation in infants is dependent on postmenstrual agePain46:177-82.


Slater R, Cantarella A, Franck L, Meek J & Fitzgerald M (2008) How well do clinical pain assessment tools reflect pain in infants? PLoS Medicine. 24;5:e129.


Slater R, Cantarella A, Gallella S, Worley A, Boyd S, Meek J & Fitzgerald M (2006) Cortical pain responses in human infantsJournal of Neuroscience. 26:3662-6.


Jones NG, Slater R, Cadiou H, McNaughton P, McMahon SB. (2004) Acid-induced pain and its modulation in humans. Journal of Neuroscience. 24:10974-9.


Reviews & Letters

Moultrie F, Slater R, Hartley C (2017) Improving the treatment of infant pain Current Opinion in Supportive and Palliative Care. Jun;11(2):112-117

Pillai Riddell R, Fitzgerald M, Slater R, Stevens B, Johnston C, Campbell-Yeo M. (2016) Using only behaviours to assess infant pain: a painful compromise? Pain. Jun 8. [Epub ahead of print]

Hartley C, Slater R. (2014) Neurophysiological measures of nociceptive brain activity in the newborn infant–the next steps. Acta Paediatr. 103(3):238-42. doi: 10.1111/apa.12490.

Wilkinson D & Slater R (2012) New insights, but also new questions, in the management of newborn pain. Pain Management. Vol. 2, No. 1, Pages 5-8.

Fabrizi L & Slater R (2012) Exploring the relationship of pain and development in the neonatal intensive care unit. Pain. 153(7):1340-1

Slater R, Boyd S, Meek J & Fitzgerald M (2011) Oral sucrose for procedural pain in infants. The Lancet. 377:27-28.

Slater R, Fitzgerald M & Meek J (2007) Can cortical responses following noxious stimulation inform us about pain processing in neonates? Seminars in Perinatology. 31:298-302.

Slater R, Boyd S, Meek J & Fitzgerald M (2006) Cortical pain responses in the infant brainPain. 123:332-4.


Book Chapters & Published Abstracts

Hartley C and Slater R. Neuroimaging of Paediatric Pain (2017) Neuroimaging of Pain. Edited by Luca Saba.

Moultrie F, Goksan S, Poorun R and Slater R. Pain in neonates and infants (2016) An Introduction to Pain and its relation to Nervous System Disorders. Edited by Anna Battaglia.

Poorun R and Slater R: The neurophysiological evaluation of nociceptive responses in neonates (2014) Oxford Textbook of Paediatric Pain. Edited by Patrick J. McGrath, Bonnie J. Stevens, Suellen M. Walker, and William T. Zempsky.

Slater R, Cantarella A, Worley A, Boyd S, Meek J & Fitzgerald M (2006) Cortical Responses to Noxious Stimulation in Preterm Infants. In: Flor H, Kalso E, Dostrovsky J, editors. Proceedings of the 11th World Congress on Pain. Seattle: IASP Press; p. 439-48.

Slater R, Cantarella A, Franck L, Meek J & Fitzgerald M (2007) How well do clinical pain assessment tools measure pain in infants? Correlating cortical and behavioural responses to heel lance in pre-term neonates. Acta Paediatrica. 96:126.

Slater R, Gallella S, Boyd S, Meek J & Fitzgerald M (2004) Noxious stimulation causes functional activation of the somatosensory cortex in newborn infants. Early Human Development. 80:171-172.